Clinical studies in palmoplantar pustulosis

Participation in research projects helps generate high-quality medical knowledge. Thanks to clinical trials, it is possible to:

• Evaluate the efficacy and safety of new therapeutic alternatives.
• Gain deeper insight into the inflammatory pathways involved in the disease.
• Study options for people with persistent or difficult-to-control flare-ups.
• Improve assessment of disease severity and treatment response.
• Analyze the impact of lesions on everyday activities and quality of life.
• Move towards strategies that are better adapted to each person’s individual characteristics.

These advances may contribute to expanding management options for palmoplantar pustulosis in future clinical practice.

Clinical studies in palmoplantar pustulosis may investigate:

• New molecules targeting specific inflammatory mechanisms.
• Therapeutic options designed to reduce the number and intensity of pustules.
• Strategies aimed at prolonging control between flare-ups.
• Alternatives for people who have not achieved a sufficient response with previous treatments.
• More precise methods for assessing disease severity and activity.

Participation requirements may vary depending on the specific project and may include factors such as:

• Age.
• Confirmation of the diagnosis.
• Number and location of the pustules.
• Duration and activity of the disease.
• Treatments used previously.
• General health status.
• Other criteria defined in the protocol.

Meeting the general requirements does not guarantee inclusion in the study. Participation must be assessed and confirmed by the research team.

Before deciding whether you would like to receive information about participating in a clinical study, it is important to consider the following:

• Participation is voluntary.
• You may decide not to participate after receiving all the information.
• You may withdraw from the study at any time, without this affecting your usual medical care.
• Investigational treatments do not guarantee an individual clinical benefit.
• Response may vary from one person to another.
• The treatments under study may involve risks or side effects.
• All studies are regulated and supervised by health authorities and independent ethics committees.
• Before participating, you will receive detailed information about the visits, tests, procedures and potential risks.

Our team is available to provide you with all the information you need in a clear, confidential and transparent manner before you decide whether you would like to participate.

Does participating in a clinical study involve any cost?

No. Treatments, visits and medical assessments directly related to the study are usually covered by the sponsor.

Is palmoplantar pustulosis an infection?

No. Although the lesions contain a whitish or yellowish material similar to pus, the pustules are considered sterile and are not usually caused by bacteria or fungi. Palmoplantar pustulosis is an inflammatory disease and is not contagious.

Is it the same as psoriasis?

Not exactly. Palmoplantar pustulosis has traditionally been included within the spectrum of pustular diseases related to psoriasis. However, it has its own characteristics and may appear without psoriasis being present in other areas of the body. Its classification and exact relationship with psoriasis continue to be studied.

What safety measures are in place?

Clinical studies follow protocols approved by ethics committees and regulatory authorities. Throughout the process, participants receive follow-up from a specialized team.

What happens if I want to leave the study?

You can withdraw from the study at any time, without having to give a reason and without it affecting your future medical care.

How is my personal data protected?

Medical and personal data are treated confidentially and in accordance with current data protection regulations.

Does meeting the general criteria guarantee participation?

No. The published criteria provide initial guidance, but the research team must assess each case and confirm that all requirements established in the protocol are met.

Where can I get more information?

If you would like to learn more about the clinical studies in palmoplantar pustulosis conducted at ICMR Research, you can contact our team confidentially:

• Through the contact form on our website.
• Through the pre-screening questionnaire.
• By emailing us at info@icmrresearch.com.
• By requesting information through the ICMR phone line.

We will respond in a personalized manner, always respecting your privacy and your right to decide freely.