ICMR

Alopecia areata

Research center in Spain (Madrid)

Clinical trials in alopecia areata

Alopecia areata is an autoimmune disease that causes hair loss in localized areas of the scalp or body. Although its progression can be unpredictable, advances in medical research are opening up new therapeutic possibilities.

At ICMR, an international medical research center based in Madrid, we participate in research projects aimed at improving the treatment of this condition. Our goal is to contribute to the development of new therapeutic strategies through rigorous and ethically supervised clinical trials.

What is alopecia areata?

Alopecia areata is an immune-mediated condition in which the immune system mistakenly attacks hair follicles, leading to their weakening and subsequent hair loss.

This disease is characterized as:

  • Inflammatory: it triggers a localized immune response targeting the hair follicle.
  • Non-scarring: follicles usually remain viable, allowing for spontaneous regrowth in some cases.
  • Unpredictable: it may present as a single patch, affect multiple areas, or progress to more extensive forms such as total or universal alopecia.

In addition to the physical effects, alopecia areata can have a significant emotional impact, often leading to decreased self-esteem or anxiety, and affecting the overall quality of life of those who experience it.

It is also now recognized that alopecia areata may be associated with other autoimmune conditions, such as thyroiditis, vitiligo, or type 1 diabetes, highlighting the need for a comprehensive medical approach.

What is a clinical trial?

A clinical trial is a type of clinical study that evaluates new treatment options to determine their efficacy, safety, and tolerability. These trials are conducted under strict ethical and scientific standards, with the aim of delivering medical advances based on solid evidence.

All studies are overseen by health authorities and independent ethics committees, ensuring the protection of participants’ rights.

Research and clinical trials in alopecia areata in Spain (Europe)
New investigational treatments for refractory or extensive alopecia areata.
ICMR – International Clinical Research Center in Alopecia Areata (Madrid)

Clinical trials in progress for alopecia areata

Studies and clinical research projects on alopecia areata

DISEASE

Alopecia areata in adolescents

Study aimed at evaluating new therapeutic options for alopecia areata in pediatric and adolescent population.

N

Patients between 6 and 18 years old

N

With a hair loss of more than 50% of the scalp

The ICMR is a leading clinical research center in Europe

GENERAL INFORMATION

Alopecia areata research project

At ICMR, we collaborate on several research projects related to alopecia areata, across different phases of clinical development. Our commitment is to contribute to scientific progress by gaining a better understanding of the disease and exploring new therapeutic options.

Current lines of research include:

  • Evaluation of new immunomodulatory treatments.
  • Studies on targeted therapies aimed at blocking specific inflammatory pathways.
  • Research on biomarkers to predict disease progression and treatment response.

All projects are conducted in accordance with international quality standards, with a strong focus on the safety and well-being of those who choose to participate.

Contributions of Clinical Research in Alopecia Areata

Clinical research plays a key role in medical progress. Thanks to clinical studies and trials, it is possible to:

  • Develop treatments that target the immune mechanisms involved.
  • Improve understanding of the disease, its triggers, and its natural progression.
  • Advance the development of personalized therapies tailored to each patient’s individual characteristics.
  • Help provide safer and more effective therapeutic options in the future.

These advances benefit both the medical community and individuals living with alopecia areata, broadening the possibilities for disease management.

Information on Available Clinical Trials

ICMR Research is currently involved in several clinical studies focused on alopecia areata, including:

  • New targeted immunomodulatory molecules.
  • Innovative treatments for extensive forms of alopecia areata (total or universal alopecia).
  • Genetic and biological research projects.

Each study has specific eligibility criteria, which may include factors such as age, disease duration, prior treatments, and overall health status.

Important considerations

Before deciding whether to participate in a clinical trial, it is essential to understand the following:

  • Participation is always voluntary and can be discontinued at any time without any consequences.
  • There is no guarantee of individual benefit; investigational treatments may produce variable outcomes.
  • All studies are conducted under strict safety regulations and are overseen by independent ethics committees.

Our team provides complete, objective, and accessible information so that each person can make a fully informed and autonomous decision.

Frequently Asked Questions About Clinical Trials in Alopecia Areata

Does it cost anything to participate in a clinical study?

No. Treatments and medical evaluations related to the trial are fully covered by the study sponsor.

What are the potential risks?

Each investigational treatment may have side effects. All potential risks are explained beforehand, and participants receive ongoing medical monitoring throughout the study.

Can I withdraw from the study if I change my mind?

Yes. Participation is voluntary and can be discontinued at any time, always respecting the participant’s decision.

How is my privacy protected?

The confidentiality of personal and medical data is strictly protected in accordance with current data protection laws.

Where can I get more information?

To learn more about the alopecia areata clinical trials currently available at ICMR Research, our support team is available through:

All inquiries will be handled confidentially and respectfully, with no obligation to participate.

ICMR

About us

ICMR is a reference center in Spain and Europe dedicated to the research of inflammatory and/or immune-mediated dermatological diseases. Promoted by the Pedro Jaén Foundation, our main objective is to transfer the highest level of science to patients who cannot find a solution to their dermatological problems with currently approved treatments.

ICMR

Research areas

At ICMR we are prepared to develop research in all dermatological indications, with special attention to:

Psoriasis

We analyze genetic and immune factors to improve the approach to this disease.

Alopecia areata

We investigate the autoimmune basis and new options that stimulate hair growth.

Hidradenitis suppurativa

We analyze genetic and immune factors to improve the approach to this disease.

Atopic dermatitis

We explore the alteration of the skin barrier and the mediators that cause inflammation.

Nodular prurigo

We study the origin of severe itching and seek therapies to alleviate the discomfort.

Vitiligo

We investigate the autoimmune process that affects melanocytes and how to recover pigmentation.

Notalgia paresthetica

We study the neuropathic origin of itching and therapies to control the symptoms.