ICMR
Atopic dermatitis
Research center in Spain (Madrid)
Clinical trials in atopic dermatitis
Atopic dermatitis is a chronic inflammatory skin disease that affects millions of people worldwide. Despite the available therapeutic options, there remains a significant need for treatments that effectively control inflammation, itching, and flare-ups.
At ICMR, a medical research center based in Madrid, we lead and collaborate on clinical research projects that explore new therapeutic alternatives through carefully designed and supervised clinical trials.
What is atopic dermatitis?
Atopic dermatitis is an immune-mediated disease that causes chronic inflammation of the skin. It typically presents as:
- Dry, red skin with intense itching.
- Recurrent flare-ups affecting different areas of the body.
- Impairment of the skin barrier, leading to infections and sensitization.
This is a complex condition influenced by multiple factors: genetic predisposition, immune system dysregulation, skin barrier deficiency, and environmental triggers.
Beyond its skin manifestations, atopic dermatitis may be associated with other atopic disorders such as allergic rhinitis, asthma, or food allergies. It also has a significant emotional impact due to persistent discomfort and the social limitations it can cause.
Today, it is considered a systemic disease that requires a comprehensive and personalized treatment approach.
What is a clinical trial?
A clinical trial is a type of clinical study that investigates new treatment, diagnostic or prevention strategies under controlled conditions.
These studies meet strict international standards to ensure the safety and rights of those who choose to participate. Approval by independent ethics committees is a fundamental requirement before initiating any research project.
Thanks to clinical trials, it is possible to scientifically validate new therapeutic options that would otherwise not be incorporated into routine medical practice.
How do clinical trials in atopic dermatitis work?
Clinical research in atopic dermatitis follows a progressive process divided into phases:
- Phase I: Initial safety assessment in a small number of volunteers.
- Phase II: Preliminary efficacy study in patients with the disease.
- Phase III: Comparison with standard treatments in large populations.
- Phase IV: Observation of how the treatment performs in real-world conditions after regulatory approval.
Throughout the trial, participants receive continuous medical check-ups and follow-up tailored to their progress.
Active clinical trials in atopic dermatitis
CONDITION
Moderate to severe atopic dermatitis
Clinical study aimed at evaluating new therapeutic options for atopic dermatitis in adults.
Patients aged 18 years or older
Atopic dermatitis affecting 10% or more of body surface area
The ICMR is a leading clinical research center in Europe
GENERAL INFORMATION
Research project in atopic dermatitis
At ICMR, we are involved in various research projects focused on the treatment and understanding of atopic dermatitis. Our goal is to contribute to improving the medical management of the disease from different perspectives.
We are currently participating in studies that investigate:
- New biological drugs targeting molecules involved in atopic inflammation.
- Oral therapies with selective mechanisms of action.
- Strategies to restore the skin barrier and reduce the chronicity of flare-ups.
Each project adheres to the highest scientific and ethical standards, with the goal of generating robust data to help advance the treatment of this disease.
Impact of clinical research in atopic dermatitis
In recent years, clinical trials have revolutionized the treatment of atopic dermatitis, but continued research remains essential.
Clinical research projects make it possible to:
- Explore new therapeutic targets that act directly on the underlying inflammation.
- Optimize existing treatments by improving their efficacy and reducing side effects.
- Better understand the relationship between atopic dermatitis and associated conditions.
- Offer treatment approaches more tailored to each patient’s individual profile.
These advances strengthen the therapeutic arsenal and open up new possibilities to improve the quality of life for people living with atopic dermatitis.
About the available clinical studies
At ICMR we are developing different clinical trials focused on atopic dermatitis, including:
- New biologic drugs in advanced stages of research.
- Innovative treatments for moderate and severe atopic dermatitis.
- Research projects combining pharmacological treatment and skin barrier restoration.
Each study has specific participation criteria, which usually depend on factors such as:
- Age and severity of atopic dermatitis.
- History of previous treatments.
- General health status.
Important considerations
Important considerations
If you are considering the possibility of participating in a clinical trial, it is essential to keep a few points in mind:
- Participation is voluntary, and may be discontinued at any time if desired.
- Not all investigational treatments have guaranteed benefits; some may have no effect or be less effective than expected.
- All studies are subject to ethical approval and regulatory oversight, ensuring the safety of participants.
At ICMR Research, we provide all the necessary information so that each person can make a fully informed and voluntary decision.
Frequently asked questions on clinical trials in atopic dermatitis
Is there a cost to participate in a clinical trial?
No. Usually, the investigational treatment and related medical evaluations are covered by the study sponsor.
Are there any risks?
As with any medical treatment, there may be side effects. Before entering a study, clear and detailed explanations of the potential risks are provided.
Can I leave the study at any time?
Yes. Participation is completely voluntary and may be discontinued at any time.
Will my information be protected?
Yes, the confidentiality of medical and personal data is protected in accordance with current data protection legislation.
Where can I get more information?
For more information about clinical studies in atopic dermatitis available at ICMR Research, you can contact our team through:
- Through the contact form on our website.
- By emailing us at info@icmrresearch.com.
- Personalized telephone attention.
We will respond to all inquiries in a confidential, respectful and non-binding manner.
About us
ICMR is a reference center in Spain and Europe dedicated to the research of inflammatory and/or immune-mediated dermatological diseases. Promoted by the Pedro Jaén Foundation, our main objective is to transfer the highest level of science to patients who cannot find a solution to their dermatological problems with currently approved treatments.
Research areas
At ICMR we are prepared to develop research in all dermatological indications, with special attention to:
Psoriasis
We analyze genetic and immune factors to improve the approach to this disease.
Alopecia areata
We investigate the autoimmune basis and new options that stimulate hair growth.
Hidradenitis suppurativa
We analyze genetic and immune factors to improve the approach to this disease.
Atopic dermatitis
We explore the alteration of the skin barrier and the mediators that cause inflammation.
Nodular prurigo
We study the origin of severe itching and seek therapies to alleviate the discomfort.
Vitiligo
We investigate the autoimmune process that affects melanocytes and how to recover pigmentation.
Notalgia paresthetica
We study the neuropathic origin of itching and therapies to control the symptoms.