ICMR
Notalgia paresthetica
Research center in Spain (Madrid)
Clinical trials on notalgia paraesthetica
Notalgia paresthetica is a neurosensory skin condition that can produce persistent symptoms of itching, stinging and sensory disturbances. Although not life-threatening, its impact on quality of life can be significant and there is as yet no definitive curative treatment.
At ICMR, an international medical research center in Madrid, we participate in research projects that seek to better understand this disease and develop new therapeutic options through rigorously designed clinical trials.
What is notalgia paresthetica?
Notalgia paresthetica is a benign neuropathic disorder that mainly affects the upper back, near the scapulae. It is characterized by:
- Localized and persistent itching.
- Burning, stinging or numbness in specific areas of the skin.
- Redness, hyperpigmentation or changes in skin texture due to continuous scratching.
This condition is thought to be caused by irritation or compression of dorsal cutaneous nerves, in many cases related to degenerative changes in the spine or postural alterations.
Although it does not compromise vital functions, it can affect emotional well-being, sleep and daily activities, especially in cases of severe and chronic pruritus.
What is a clinical trial?
A clinical trial is a type of clinical study designed to evaluate new treatment options, with the objective of determining their efficacy, safety and tolerability profile.
Prior to implementation, each trial must be approved by independent ethics committees and regulatory bodies, ensuring compliance with regulations to protect the rights of participants.
Thanks to clinical trials, new therapeutic approaches can be validated that, in the future, may improve the management of diseases such as notalgia paresthetica.
How do clinical trials in notalgia paresthetica work?
Clinical research follows a well-defined structure that includes several phases:
- Phase I: Preliminary safety evaluation of a new treatment in a small group of volunteers.
- Phase II: Study of initial efficacy and dose adjustment in patients with the disease.
- Phase III: Large-scale comparison with existing therapies or placebo.
- Phase IV: Analysis under real conditions after commercial authorization.
Throughout the process, participants are carefully monitored to ensure their safety and to collect accurate information on the effects of the treatment.
Active clinical trials in notalgia paraesthetica
Ongoing clinical trial
Notalgia paresthetica
Pacientes adultos mayores de 18 años
The ICMR is a leading clinical research center in Europe
GENERAL INFORMATION
Research projects in notalgia paresthetica
At ICMR, we are working on several research projects aimed at finding more effective therapeutic alternatives for the management of the symptoms of notalgia paresthetica.
Currently, we participate in studies focused on:
- New neuromodulatory treatments acting on neuropathic itch pathways.
- Pharmacological strategies to reduce inflammation of involved peripheral nerves.
- Treatment combinations aimed at improving the quality of life in people with localized chronic pruritus.
All our research work is conducted under strict scientific and ethical quality standards.
Contributions of clinical research in notalgia paresthetica.
Clinical research has allowed great advances in the field of sensorineural diseases. In the case of notalgia paresthetica, clinical studies offer the possibility of:
- To expand knowledge of the neurological mechanisms involved in localized pruritus.
- To develop drugs that act more precisely on the source of chronic itching.
- Optimize symptom control and minimize the need for prolonged treatments that may have side effects.
- Improve the quality of life and well-being of affected persons.
These advances make it possible to design more effective and personalized strategies for the management of this disease.
Information on Available Clinical Trials
ICMR Research is currently developing several clinical trials focused on the treatment of notalgia paresthetica, including:
- Studies with specific neuromodulatory molecules.
- Research on innovative topical and systemic therapies.
- Projects aimed at the evaluation of itch relief and functional improvement.
Each study has defined participation requirements, which may depend on:
- Duration and intensity of symptoms.
- Medical history and previous treatments.
- Other health factors that are evaluated individually.
Relevant aspects to consider
If you are considering receiving information about participation in a clinical trial, it is important to keep in mind that:
- Participation is free and voluntary and may be discontinued at any time.
- No personal benefits are guaranteed as a result of the research treatment.
- All trials are conducted with ethical approval and under the supervision of competent health agencies.
At ICMR Research we provide complete, objective and transparent information to facilitate an informed decision.
Frequently asked questions about clinical trials in notalgia paraesthetica
Is there any cost for participants?
No. Treatment and medical evaluations related to the trial are covered by the study sponsor.
What risks are associated with the studies?
Each research treatment may involve risks or side effects, which are explained in detail before signing the informed consent form.
Can I withdraw from the study?
Yes, participation may be discontinued at any time, with no consequences and no need to justify the decision.
How is my personal data protected?
All data is treated confidentially and in accordance with current data protection legislation.
Where can I get more information?
If you would like to know more about the clinical trials on notalgia paraesthetica developed at ICMR Research, please contact us:
- Through the contact form on our website.
- Email to info@icmrresearch.com.
- By contacting us directly through our customer service number.
Each consultation will be handled in a personalized, confidential and non-binding manner.
About us
ICMR is a reference center in Spain and Europe dedicated to the research of inflammatory and/or immune-mediated dermatological diseases. Promoted by the Pedro Jaén Foundation, our main objective is to transfer the highest level of science to patients who cannot find a solution to their dermatological problems with currently approved treatments.
Research areas
At ICMR we are prepared to develop research in all dermatological indications, with special attention to:
Psoriasis
We analyze genetic and immune factors to improve the approach to this disease.
Alopecia areata
We investigate the autoimmune basis and new options that stimulate hair growth.
Hidradenitis suppurativa
We analyze genetic and immune factors to improve the approach to this disease.
Atopic dermatitis
We explore the alteration of the skin barrier and the mediators that cause inflammation.
Nodular prurigo
We study the origin of severe itching and seek therapies to alleviate the discomfort.
Vitiligo
We investigate the autoimmune process that affects melanocytes and how to recover pigmentation.
Notalgia paresthetica
We study the neuropathic origin of itching and therapies to control the symptoms.